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Cannabidivarin (CBDV) is a non-psychoactive cannabinoid found in Cannabis. It is a homolog of cannabidiol (CBD), with the side-chain shortened by two methylene bridges (CH2 units). Plants with relatively high levels of CBDV have been reported in feral populations of C. indica ( = C. sativa ssp. indica var. kafiristanica) from northwest India, and in hashish from Nepal.
Similarly to CBD, it has 7 double bond isomers and 30 stereoisomers (see: Cannabidiol#Double bond isomers and their stereoisomers). It is not scheduled by Convention on Psychotropic Substances. It is being actively developed by GW Pharmaceuticals because of a demonstrated neurochemical pathway for previously-observed anti-epileptic and anti-convulsive action.
- Turner, C.E., P. C. Cheng, G.S. Lewis, M.H.Russell and G.K. Sharma. 1979. Constituents of Cannabis sativa XV: Botanical and chemical profile of Indian variants. Planta medica 37(3): 217-225.
- Hillig, Karl W. and Paul G. Mahlberg. 2004. A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). American Journal of Botany 91(6): 966-975.
- Amada, N; Yamasaki, Y; Williams, C. M.; Whalley, B. J. (2013). "Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression". PeerJ 1: e214. doi:10.7717/peerj.214. PMC 3840466. PMID 24282673.
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- Erowid Compounds found in Cannabis sativa
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