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Cannabipiperidiethanone structure.png
Systematic (IUPAC) name
Clinical data
Legal status
CAS number 1345970-43-5
ATC code ?
ChemSpider 27330303
Chemical data
Formula C24H28N2O2 
Molecular mass 376.490

Cannabipiperidiethanone, (CPE, or 1-(N-methylpiperidin-2-ylmethyl)-3-(2-methoxyphenylacetyl)indole), is a synthetic cannabinoid that has been found as an ingredient of "herbal" synthetic cannabis blends sold in Japan, alongside JWH-122 and JWH-081. Its binding affinity was measured at the CB1 and CB2 receptors and it was found to have an IC50 of 591nM at CB1 and 968nM at CB2, making it 2.3x and 9.4x weaker than JWH-250 at these two targets respectively.[1]

See also[edit]


  1. ^ Uchiyama N, Kikura-Hanajiri R, Goda Y (2011). "Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB₁ and CB₂ receptors". Chemical & Pharmaceutical Bulletin 59 (9): 1203–5. doi:10.1248/cpb.59.1203. PMID 21881274.