From Wikipedia, the free encyclopedia
Jump to: navigation, search
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
Legal status
  • Prescription only
Routes Oral
Pharmacokinetic data
Excretion Renal
CAS number 486-17-9
ATC code N05BB02
PubChem CID 10240
ChemSpider 9823 YesY
UNII H93K9455DD YesY
KEGG D07316 YesY
Chemical data
Formula C21H29NS2 
Mol. mass 359.594 g/mol
 YesY (what is this?)  (verify)

Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine.[1]

A 2004 study suggested captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.[1]

See also[edit]


  1. ^ a b Mercier-Guyon C, Chabannes JP, Saviuc P (2004). "The role of captodiamine in the withdrawal from long-term benzodiazepine treatment". Curr Med Res Opin 20 (9): 1347–55. doi:10.1185/030079904125004457. PMID 15383182.  Free full text with registration