Carapichea ipecacuanha is a species of flowering plant in the Rubiaceae family. It is native to Costa Rica, Nicaragua, Panama, Colombia, Brazil. Its common name, ipecacuanha (Portuguese pronunciation: [ipe̞kɐkuˈɐ̃ɲɐ]), is derived from the Tupi ipega'kwãi, or "road-side sick-making plant". The plant has been discussed under a variety of synonyms over the years by various botanists. The roots were used to make syrup of ipecac, a powerful emetic.
The part of ipecacuanha used in medicine is the root, which is simple or divided into a few branches, flexuous, and is composed of rings of various size, somewhat fleshy when fresh, and appearing as if closely strung on a central woody cord. The different kinds known in commerce (gray, red, brown) are all produced by the same plant, the differences arising from the age of the plant, the mode of drying, etc. Various other plants are used as substitutes for it.
Ipecacuanha was known to Europe by the mid 17th century. Nicholas Culpeper, an English botanist, herbalist, and physician, compared Ipecacuanha to the herb Orach in his book, Complete Herbal & English Physician, published in 1653. One of the first recorded shipments of Ipecacuanha to Europe was in 1672, by a traveler named Legros. Legros imported some quantity of the root to Paris from South America. In 1680, a Parisian merchant named Garnier possessed some 68 kilograms (150 pounds) of the substance and informed the physician Jean Claude Adrien Helvetius (1685–1755) of its power in the treatment of dysentery. Helvetius was granted sole right to vend the remedy by Louis XIV, but sold the secret to the French government, who made the formula public in 1688.
Ipecacuanha has a long history of use as an emetic, for emptying the stomach in cases of poisoning. It has also been used as a nauseant, expectorant, and diaphoretic, and was prescribed for conditions such as bronchitis. The most common and familiar preparation is syrup of ipecac, which was commonly recommended as an emergency treatment for accidental poisoning until the final years of the 20th century. Ipecacuanha was also traditionally used to induce sweating. A common preparation for this purpose was Dover's powder.
In the 19th Century, women prisoners at the Cascades Female Factory, Tasmania, were routinely given "a grain or so of ipecacuanha" as a precaution, especially "upon ladies with gross health and fiery temperaments" (Daniels 129).
The following plants have been used as substitutes for ipecacuanha.
- Euphorbia ipecacuanhae, wild ipecacuanha from North America
- Sarcostemma glaucum, a Venezuelan plant of the Apocynaceae family
- Tylophora asthmatica, in India
- Gillenia stipulata, American ipecac
- Richardsonia pilosa, Richardsonia rosea, Psychotria emetica and various species of Ionidium have been used too
Appearances in popular culture
- Lord Peter Wimsey's sister takes ipecacuanha to appear sick in the Dorothy Sayers mystery novel Clouds of Witness, 1926.
- Guybrush Threepwood used Ipecacuanha syrup (made by combining a flower from the Ipecacuanha with maple syrup) in order to escape from the giant snake that swallowed him in Monkey Island 3: The Curse of Monkey Island video game.
- The rake Lovelace takes ipecacuanha to feign illness and trick the titular character into caring for him in the novel, Clarissa, or, the History of a Young Lady, an epistolary novel by Samuel Richardson, published in 1748
- Ipecacuanha on www.henriettesherbal.com
- genealogy of the family
- "Policy statement: Poison treatment in the home". Pediatrics 112 (5): 1182–1185. November 2003. doi:10.1542/peds.112.5.1182. PMID 14595067.
- Daniels, Kay. Convict Women. Allen & Unwin, 1998, p. 129.
|Wikisource has the text of the 1921 Collier's Encyclopedia article Ipecacuanha.|
- R05 Therapeutic classification