Carboxyfluorescein
| Carboxyfluorescein | |
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Other names
6-FAM |
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| Identifiers | |
| CAS number | 3301-79-9  |
| ChemSpider | 69262 |
| ChEBI | CHEBI:39073 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C21H12O7 |
| Molar mass | 376.32 g mol−1 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Carboxyfluorescein refers to two fluorescent dyes with an excitation and emission of 492/517 nm, respectively. They are commonly used as a tracer agents. The dyes are membrane-impermeant and can be loaded into cells by microinjection or scrape loading.[1] It can be incorporated into liposomes, and allow for the tracking of liposomes as they pass through the body. In addition, carboxyfluorescein has been used to track division of cells.[2]
Popular derivatives for cell tracing purposes are Carboxyfluorescein diacetate succinimidyl ester (CFDA-SE) and Carboxyfluorescein succinimidyl ester (CFSE).
[edit] See also
[edit] References
- ^ Molecular Imaging Products Company (2005-08-26). "5-(and-6)-Carboxyfluorescein (5-(and-6)- FAM,mixed isomer) 100mg". http://store.mipcompany.com/510.html. Retrieved 2006-08-26.
- ^ Parish, Christopher (December 1999). "Fluorescent dyes for lymphocyte migration and proliferation studies". Immunology and Cell Biology. Blackwell Synergy. http://www.blackwell-synergy.com/doi/abs/10.1046/j.1440-1711.1999.00877.x. Retrieved 2006-08-26.[dead link]
