Verrucous carcinoma
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| Verrucous carcinoma | |
|---|---|
| Classification and external resources | |
 An exophytic and hyperkeratotic mass that discharged malodorous debris through several sinus tracts |
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| ICD-O: | M8051/3 |
| eMedicine | derm/452 |
| MeSH | D018289 |
Verrucous carcinoma (also known as Carcinoma cuniculatum[1]:654, and Ackerman tumor[2]) is an uncommon variant of squamous cell carcinoma.[3] This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer."
Most patients with verrucous carcinoma have a good prognosis. Local recurrence is not uncommon, but metastasis to distant parts of the body is rare. Patients with oral verrucous carcinoma may be at greater risk of a second oral squamous cell carcinoma, for which the prognosis is worse.
Contents |
[edit] Classification
Verrucous carcinoma may be divided into the following four types:[4]:742
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- Type I, also known as Oral florid papillomatosis
- Type II, also known as Anogential type verrucous carcinoma
- Type III, also known as Epithelioma cuniculatum
- Type IV
[edit] Definition
It’s a diffuse, papillary, non metastasizing, well differentiated, malignant neoplasm of epidermis or oral epithelium. It is also known as an Ackerman tumor.
[edit] Etiology
This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer."
[edit] Clinical features
- age- usually over 60 yrs
- sex- males are more prone
- site- gingiva, buccal mucosa, alveolar mucosa, hard palate, floor of the mouth, larynx, oesophagus, penis, vagina, scrotum.
- clinical presentation-
- It’s a slow growing, diffuse, exophytic lesion usually covered by Leukoplakik patches.
- Invasive lesions quickly invade bones
- It is rapidly become fixed with underlying periosteum and cause gradual destruction of jaw bone.
- Enlarged regional lymph nodes
- Lesion shows painful multiple rugae like folds and deep clefts between them.
[edit] Treatment
Surgical excision or laser therapy
[edit] See also
[edit] References
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0721629210.
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ Ridge JA, Glisson BS, Lango MN, et al. "Head and Neck Tumors" in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) Cancer Management: A Multidisciplinary Approach. 11 ed. 2008.
- ^ Freedberg, et. al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
[edit] External links
- eMedicine.com article
- Maxillofacial Center for Education & Research article
- Cancer Management Handbook: Head and Neck Tumors
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