Cardiotoxin III
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Cardiotoxin III (CTX III, also known as cytotoxin 3) is a sixty amino-acid polypeptide toxin from the Taiwan Cobra Naja naja atra.
Recent evidence has shown that CTX III may induce apoptosis in K562 cells via the release of cytochrome c.[1]
This protein belongs to large family of snake venom toxins.[2]
[edit] References
- ^ Yang SH, Chien CM, Lu MC, Lu YJ, Wu ZZ, Lin SR (July 2005). "Cardiotoxin III induces apoptosis in K562 cells through a mitochondrial-mediated pathway". Clin. Exp. Pharmacol. Physiol. 32 (7): 515–20. doi:10.1111/j.1440-1681.2005.04223.x. PMID 16026508. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0305-1870&date=2005&volume=32&issue=7&spage=515.
- ^ "Superfamily » 2.2.39. Snake toxin-like (2 families) - Orientations of Proteins in Membranes (OPM) database". http://opm.phar.umich.edu/families.php?superfamily=55. Retrieved 2008-12-13.
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