Casoni test

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The Casoni test is a skin test used in the diagnosis of hydatid disease. The test involves the intradermal injection of 0.25 ml of sterilised fluid from hydatid cysts. A wheal response occurring at the injection site within 20 minutes is considered positive. (Immediate hypersensitivity). Delayed hypersensitivity reaction usually read after 18-24 hours. [1] The test is positive in about 90% of cases of hydatid disease affecting the liver, but positive in less than 50% of patients with hydatid disease elsewhere in the body; false positive results are also common. Consequently, serological tests are now generally used.[2]

The test was described in 1912 by Tomaso Casoni.[3]

References[edit]

  1. ^ Robert A. Evans. Special Tests: The Procedure and Meaning of the Commoner Tests in Hospital, page 14. Elsevier Health Sciences, 2003. ISBN 978-0-7234-3289-0.
  2. ^ Richard Ravel. Clinical laboratory medicine, page 291. Elsevier Health Sciences, 1994. ISBN 978-0-8151-7148-5.
  3. ^ Casoni T. La diagnosi biologica dell'echinococcosi umana mediante l'introdermoreazione. Folia Clinica Chimica e Microscopica; 1912: 4