Cau-Cau River is minor river in the city of Valdivia, southern Chile. Cau-Cau River acts as a regulating channel between Cruces River and Calle-Calle River forming the Isla Teja island in front of the city centre. It confluence with Calle-Calle River marks the beginning of Valdivia River.
The subsidence caused by the 1960 Valdivia earthquake caused a permanent flooding of parts botanical garden of the Austral University of Chile that were next to Cau-Cau River.
Coordinates: 39°47′52″S 73°15′23″W / 39.79778°S 73.25639°W