Cefacetrile

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Cefacetrile
Cefacetrile.svg
Systematic (IUPAC) name
(6R,7R)-3-(acetyloxymethyl)-7-[(2-cyanoacetyl)amino]-
8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-
carboxylic acid
Clinical data
Trade names Celospor, Celtol, Cristacef
AHFS/Drugs.com International Drug Names
Legal status Prescription only
Routes Intravenous, intramuscular, intramammary
Pharmacokinetic data
Protein binding 23 to 38%
Half-life 1.2 hours
Excretion Renal (72%)
Identifiers
CAS number 10206-21-0 YesY
ATC code J01DB10 QJ51DB10
PubChem CID 91562
DrugBank DB01414
ChemSpider 82675 YesY
UNII FDM21QQ344 YesY
KEGG D07629 YesY
Chemical data
Formula C13H13N3O6S 
Mol. mass 339.325 g/mol
 YesY (what is this?)  (verify)

Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. It is a bacteriostatic antibiotic.[1][2] Cefacetrile is marketed under the trade names Celospor, Celtol, and Cristacef,[3] and as Vetimast for the treatment of mammary infections in lactating cows.[2]

References[edit]

  1. ^ "Cefacetrile Summary Report". European Medicines Agency, Committee for Veterinary Medicinal Products. 1998. 
  2. ^ a b Haberfeld, H, ed. (2007). Austria-Codex (in German) (2007/2008 ed.). Vienna: Österreichischer Apothekerverlag. ISBN 3-85200-183-8. 
  3. ^ Horiuchi, N.; Oyakawa, Y.; Oka, R.; Fujiwara, T. (1980). "Clinical evaluation of cephacetrile (Celtol) for respiratory infections (author's transl)". The Japanese journal of antibiotics 33 (10): 1145–1155. PMID 7206219.  edit