CMRT was founded as the Corridor Transportation Corporation in May 1987 by the Baltimore Washington Corridor Chamber, and began its transit operation as Connect-a-Ride two years later with nine buses serving five routes. The non-profit organization gained independence and changed its name in the early 2010 timeframe, and the bus service rebranded to the same name in early 2013.
In 2014, Howard County initiated its own Regional Transit Agency of Central Maryland, recruiting Anne Arundel County to join. CMRT bid on providing services to these regions after July 1, but lost to First Transit.
Despite no longer running transit operations as of July 1, 2014, CMRT still operates as a 501(c)(3), nonprofit organization, specifically dedicated to providing mobility management services such as Travel Training and a website and call center branded the Transportation Resource Information Point. CMRT's Travel Training program is "a comprehensive training program designed to teach people the necessary skills to travel safely and independently on fixed-route public transportation." and is "...intended for individuals with disabilities, senior citizens, students and low-income families." The Transportation Resource Information Point is a one-call, one-click resource designed to provide regional transit information throughout Central Maryland. Both programs serve a 6-county region including Anne Arundel, Baltimore, Carroll, Harford, Howard, and Prince George's Counties, including the City of Baltimore.