The Centre Avenue YMCA Building located at 2621 Centre Avenue in the Middle Hill District neighborhood of Pittsburgh, Pennsylvania, was built in 1922. A sign on the building says the following: "Centre Avenue YMCA - This building was erected in 1922 to house the only YMCA for African-Americans in Western Pennsylvania. The Centre Avenue YMCA served not only as one of the only recreational areas facilities for African-Americans from the 1920s through the 1950s, but was also a center of social and cultural life in the community, and was famous for free symposiums held here during the 1930s and '40s with nationally prominent African-Americans. Pittsburgh Historic Review Commission. Marker dedicated 1994." The building was added to the List of City of Pittsburgh historic designations on August 8, 1995.