- For the region of Burkina Faso, see Centre-Sud Region.
Centro Sur Province is a province of Equatorial Guinea. Its capital is Evinayong.
Centro Sur borders Gabon's Estuaire Province in the southwest and Woleu-Ntem Province in the southeast, and Cameroon's South Province in the north. Domestically, it borders Kié-Ntem Province in the northeast, Wele-Nzas Province in the southeast, and Litoral Province in the west. Centro Sur Province contains three main towns, which are Akurenam, Niefang and Evinayong.
Coordinates: 1°33′N 10°17′E / 1.55°N 10.29°E