Cephaeline

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Not to be confused with cephalin.
Cephaeline
Cephaeline.svg
Names
IUPAC name
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol
Other names
Cepheline; Desmethylemetine; Dihydropsychotrine
Identifiers
483-18-1 YesY
ChEMBL ChEMBL255708 N
ChemSpider 390702 N
Jmol-3D images Image
PubChem 442195
442195
UNII QA971541A1 N
Properties
C28H38N2O4
Molar mass 466.61 g·mol−1
Appearance White silky crystals
Solubility in ethanol Soluble[vague]
Hazards
Main hazards Emetic / poisonous
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine.

Poison treatment[edit]

Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3]

References[edit]

  1. ^ Lara, Alfonso; Valverde, Roberto; Gomez, Luis; Hidalgo, Nancy (July 1, 2003). "Micropropagacion de la planta medicinal psychotria acuminata". Agronomía Costarricense. Retrieved 26 December 2009. 
  2. ^ "Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel.". Chemical Business Newsbase. November 14, 2000. Retrieved 26 December 2009. 
  3. ^ "Policy statement: Poison treatment in the home". Pediatrics 112 (5): 1182–1185. November 2003. doi:10.1542/peds.112.5.1182. PMID 14595067. Retrieved 31 December 2009.