Cefalotin

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Cefalotin
Cefalotin.svg
Systematic (IUPAC) name
(6R,7R)-3-[(acetoxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a682860
Pregnancy cat. A (AU)
Legal status Prescription Only (S4) (AU) POM (UK)
Routes IV
Pharmacokinetic data
Bioavailability n/a
Protein binding 65 to 80%
Metabolism Hepatic
Half-life 30 minutes to 1 hour
Excretion Renal
Identifiers
CAS number 153-61-7 YesY
ATC code J01DB03
PubChem CID 6024
DrugBank DB00456
ChemSpider 5802 YesY
UNII R72LW146E6 YesY
KEGG D07635 YesY
ChEBI CHEBI:124991 YesY
ChEMBL CHEMBL617 YesY
Chemical data
Formula C16H16N2O6S2 
Mol. mass 396.44 g/mol
 YesY (what is this?)  (verify)

Cefalotin (INN) /ˌsɛfəˈltɨn/ or cephalothin (USAN) /ˌsɛfəˈlθɨn/ is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed (1964) and continues to be widely used. It is an intravenously administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly).

See also[edit]