Chamazulene

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Chamazulene
Chamazulene.svg
Identifiers
CAS number 529-05-5 YesY
PubChem 10719
ChemSpider 10268
Jmol-3D images Image 1
Properties
Molecular formula C14H16
Molar mass 184.28 g mol−1
Appearance Blue oil[1]
Density 0.9883 (at 20 °C)[1]
Boiling point 161 °C (at 12 mmHg)[1]
Hazards
LD50 3 g/kg (i.m., mouse)[1]
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Chamazulene is an aromatic chemical compound with the molecular formula C14H16 found in a variety of plants including in chamomile (Matricaria chamomilla), wormwood (Artemisia absinthium), and yarrow (Achillea millefolium).[1] It is a blue-violet derivative of azulene which is biosynthesized from the sesquiterpene matricin.[2]

Chamazulene has anti-inflammatory properties in vivo.[2]

References[edit]

  1. ^ a b c d e The Merck Index, 11th Edition, 2031
  2. ^ a b Safayhi, H; Sabieraj, J; Sailer, ER; Ammon, HP (1994). "Chamazulene: An antioxidant-type inhibitor of leukotriene B4 formation". Planta medica 60 (5): 410–3. doi:10.1055/s-2006-959520. PMID 7997466.