Charles Alexander was a four-year letterwinner on the LSU Tigers football team. He was selected as a first-team All-American and All-SEC in 1977 and 1978. In 1977 he was selected the SEC Most Valuable Player by the Nashville Banner. Alexander set nine SEC records, tied one and set 27 LSU records during his college career. He still holds the LSU records for most rushes in a game (43), most yards in a season (1,686) and most yards gained per game in a season (153.3).
Alexander set two Sun Bowl rushing records, carrying 31 times for 197 yards, as he won Offensive Player of the Game honors in the 1977 Sun Bowl. Despite Alexander's efforts, LSU fell to Stanford 24-14. He played his last game as a Tiger in the 1978 Liberty Bowl. Alexander gained 133 yards on 24 carries in the 20-15 loss to Missouri. In 1989, Alexander was inducted into the LSU Athletic Hall of Fame.