||This biographical article needs additional citations for verification. (February 2013)|
|Charles L. Sawyers|
|Born||Charles Lazelle Sawyers
1959 (age 55–56)
|Education||Johns Hopkins University|
|Institutions||Memorial Sloan-Kettering Cancer Center
Howard Hughes Medical Institute
|Notable prizes||Lasker Clinical Award (2009)
BBVA Foundation Frontiers of Knowledge Award (2014)
Charles L. Sawyers (//) is an investigator of the Howard Hughes Medical Institute and a physician-scientist at Memorial Sloan-Kettering Cancer Center. His work in the lab builds on the success of molecularly targeted cancer drugs with a focus on developing a new generation of treatment options for patients.
Sawyers holds the Marie-Josée and Henry R. Kravis Chair in Human Oncology and Pathogenesis Program. Sawyers is the recipient of numerous awards including the 2009 Lasker Clinical Award, which recognized him for his part in advancing treatments for chronic myeloid leukemia (CML), a relatively rare disease that strikes about 5,000 people per year in the United States. He played a key role in the development of imatinib (Gleevec) and dasatinib (Sprycel), two drugs that together have transformed CML from a fatal cancer into one that is nearly always treatable. Imatinib was approved by the US Food and Drug Administration in 2001, and dasatinib was approved in 2006.
Using his clinical understanding of treating CML as well his expertise from studying it in the laboratory, Dr. Sawyers helped design the first clinical trial for imatinib, including selecting which patients were most likely to benefit from the drug. Along with Brian J. Druker of Oregon Health and Science University and Moshe Talpaz of The University of Texas M.D. Anderson Cancer Center.
Prior to Memorial Sloan-Kettering, Sawyers worked at UCLA's Jonsson Cancer Center for nearly 18 years. He has a Bachelor's degree in history from Princeton University and an M.D. from Johns Hopkins University. He is married with two children and lives in New York City.
- BBVA Foundation Frontiers of Knowledge Award in Biomedicine along with Tony Hunter and Joseph Schlessinger (2014)
- Hope Funds for Cancer Research Award of Excellence for Clinical Development (2014)
- Breakthrough Prize in Life Sciences (2013)
- Lasker-Debakey Clinical Medical Research Award
- Doris Duke Distinguished Clinical Scientist Award
- Richard and Hinda Rosenthal Foundation Award, American Association for Cancer Research
- David A. Karnofsky Memorial Award, American Society of Clinical Oncology
- Dorothy P. Landon–AACR Prize for Translational Cancer Research
- Howard Hughes Medical Institute, Annual Scientific Report, The Institute, 1990, p. 507.
- "2009 Lasker Awards Honor Trailblazers in Medical Research and Public Service". forbes.com. 2009-09-14. Retrieved 2009-11-11.[dead link]
- Memorial Sloan-Kettering Cancer Center - Biography, Lab Description
- Howard Hughes Medical Institute - Biography, Lab Description
- Video:Talk by Sawyers at the NIH-Lasker Clinical Research Scholars Symposium, March 31, 2011.
- Video:Speaking to Katie Couric regarding Stand Up 2 Cancer - @KatieCouric, CBS news, September 8, 2010
- Quoted: New Drugs Stir Debate on Rules of Clinical Trials, New York Times, September 19, 2010
- Quoted: What can we learn from curable cancers? Newsweek, September 7, 2010
- Video: Speaking with Charlie Rose: A discussion about Cancer Treatments, October 1, 2009