The Charysh River (Russian: Чарыш) is a 547-kilometre (340 mi) long river in south-western Siberia in Russia, flowing into the left bank of the Ob River. Its source is in the Korgon mountains in the Republic of Altai, then descends into the pre-altaic depression in the Altai Krai, and it flows into the Ob 100 kilometres (62 mi) upstream of the regional capital of Barnaul.
Its watershed is 22,200 square kilometres (8,600 sq mi) in area.
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