Little was elected as a Democrat to the Sixty-ninth Congress (March 4, 1925 – March 4, 1927). He was an unsuccessful candidate for reelection in 1926 to the Seventieth Congress. He resumed the practice of law. He was an unsuccessful candidate for Governor of Kansas in 1928. He died in Olathe, Kansas, September 29, 1952. He was interred in Olathe Cemetery.