Chauncey Depew Leake (September 5, 1896 – January 11, 1978) was an American pharmacologist, medical historian and ethicist. Leake received a bachelor’s degree with majors in biology, chemistry, and philosophy from Princeton University. He received his M.S. (1920) and Ph.D. (1923) from the University of Wisconsin in pharmacology and physiology.
Leake discovered the anaesthetic divinyl ether and provided a translation of De motu cordis after being treated by the ophthalmologist Carl Koller.