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Chemical evolution may refer to:
- Stellar nucleosynthesis, the creation of chemical elements by stellar thermonuclear fusion or supernovae
- Abiogenesis, the transition from nonliving elements to living systems
- Molecular evolution, evolution at the scale of molecules
- Gas evolution reaction, the process of a gas bubbling out from a solution
- Oxygen evolution, the process of generating molecular oxygen through chemical reaction
- Cosmochemistry (or Astrochemistry), the study of the chemical composition of matter in the universe, including complex organics, and the processes that led to those compositions.
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