Chiastic Slide was released on 24 February 1997. It did not receive a release in the United States until Warp Records began distributing its own releases there in 2001. Autechre produced five remixes of the fourth track, "Cichli", on their subsequent EPCichlisuite (1997). The sleeve was designed by Sheffield-based design agency The Designers Republic.
Allmusic critic John Bush panned Chiastic Slide as being an underwhelming follow-up to 1995's groundbreaking Tri Repetae, saying it was too repetitive and lacked ideas. Tim Barr in Techno: the Rough Guide called Chiastic Slide "The aural equivalent of being at the bottom of the sea." He went on to say the album was "Dark, claustrophobic... yet full of strange beauty".