Chile–Uruguay relations are foreign relations between Chile and Uruguay. Chile has an embassy in Montevideo. Uruguay has an embassy in Santiago.
Historically, both countries were part of the Spanish Empire until the early 19th century. Both countries are full members of the Group of 77, of the Rio Group, of the Latin American Integration Association, of the Association of Spanish Language Academies, of the Organization of American States, of the Organization of Ibero-American States and of the Union of South American Nations.