Chiquimula is a city in Guatemala. It serves both as the capital of the department of Chiquimula and as the municipal seat for the surrounding municipality of the same name. It is some 174 km from Guatemala City and is in Guatemala often called "La perla del oriente" (the oriental pearl).
The official population according to the 2002 census is 79,815 inhabitants, although it is expected that the population has increased dramatically in 2010. It is the most populous city of eastern Guatemala.