Chloromethyl methyl ether
From Wikipedia, the free encyclopedia
| Chloromethyl methyl ether[1] | |
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Other names
MOM-Cl, CMME |
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| Identifiers | |
| CAS number | 107-30-2  |
| ChemSpider | 7576 |
| KEGG | C19160  |
| Properties | |
| Molecular formula | C2H5ClO |
| Molar mass | 80.51 g mol−1 |
| Density | 1.06 g/mL |
| Boiling point |
328-330 °K, 55-57 °C |
| Hazards | |
| R-phrases | R11 R20/21/22 R45 |
| S-phrases | S45 S53 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Chloromethyl methyl ether (CMME) is a compound with formula CH3OCH2Cl. It is a chloroalkyl ether. It is used as an alkylating agent and industrial solvent to manufacture dodecylbenzyl chloride, water repellents, ion-exchange resins, polymers, and as a chloromethylation reagent. In organic synthesis, it is used for introducing the methoxymethyl (MOM) protecting group.[2], and is thus often called MOM-Cl or MOM chloride.
An alternative method to prepare a MOM ether is by using dimethoxymethane.
CMME is a known human carcinogen.[3] Chronic exposure can increase the incidence of respiratory cancers, including small cell carcinoma. [4]
[edit] References
- ^ Sigma-Aldrich
- ^ Protective Groups in Organic Synthesis, T. W. Greene and P. G. M. Green, 3rd Edition, pages 27-33. ISBN 0-471-16019-9
- ^ bis(Chloromethyl) Ether and Technical-Grade Chloromethyl Methyl Ether CAS Nos. 542-88-1 and 107-30-2 Report on carcinogens, eleventh edition
- ^ "Chloromethyl methyl ether". U.S. Environmental Protection Agency, Integrated Risk Information System. 7 March 2011. Accessed 3 May 2011.
