Chlorotrianisene

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Chlorotrianisene
Chlorotrianisene.svg
Systematic (IUPAC) name
1,1',1''-(2-chloroethene-1,1,2-triyl)tris(4-methoxybenzene); 11-chloro-4,13-dimethoxy-12-(p-methoxyphenyl)stilbene
Clinical data
Trade names Tace
AHFS/Drugs.com Multum Consumer Information
Pregnancy cat.
Legal status
  • Discontinued
Routes Oral
Pharmacokinetic data
Protein binding 50 to 80%
Identifiers
CAS number 569-57-3 YesY
ATC code G03CA06
PubChem CID 11289
DrugBank DB00269
ChemSpider 10815 YesY
UNII 6V5034L121 YesY
KEGG D00269 YesY
ChEBI CHEBI:3641 YesY
ChEMBL CHEMBL1200761 N
Chemical data
Formula C23H21ClO3 
Mol. mass 380.864 g/mol
 N (what is this?)  (verify)

Chlorotrianisene (trade name Tace) is a non-steroidal synthetic estrogen that was formerly used for the treatment of menopause, deficiencies in ovary function, and prostate cancer.[1][2]

Synthesis[edit]

Chlorotrianisene synthesis:[3][4]

See also[edit]

References[edit]

  1. ^ Drugs.com: Chlorotrianisene
  2. ^ Yuen, B. H.; Pendleton, H. J.; Blair, S. (1977). "Efficacy of bromocriptine and chlorotrianisene in preventing postpartum lactation". Canadian Medical Association journal 117 (8): 919–921. PMC 1880136. PMID 334356.  edit
  3. ^ GB 561508 
  4. ^ R. S. Shelton and M. G. VanCampen, U.S. Patent 2,430,891 (1947).