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Systematic (IUPAC) name
Clinical data
AHFS/ Micromedex Detailed Consumer Information
Legal status
Routes Oral, IV, topical
Pharmacokinetic data
Bioavailability 30%
Protein binding 50 to 55%
Metabolism Hepatic (75%)
Half-life 5.6 to 9 hours
Excretion Renal and biliary
CAS number 57-62-5 YesY
ATC code A01AB21 D06AA02 J01AA03 S01AA02 QG51AA08 QJ51AA03
ChemSpider 10469370 YesY
KEGG D07689 YesY
Chemical data
Formula C22H23ClN2O8 
Molecular mass 478.88 g/mol
 N (what is this?)  (verify)

Chlortetracycline (trade name Aureomycin, Lederle) is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 by Benjamin Minge Duggar working at Lederle Laboratories under the supervision of Yellapragada Subbarow. Duggar identified the antibiotic as the product of an actinomycete he cultured from a soil sample collected from Sanborn Field at the University of Missouri.[1] The organism was named Streptomyces aureofaciens and the isolated drug, Aureomycin, because of their golden color.

In veterinary medicine, chlortetracycline is commonly used to treat conjunctivitis in cats.[2]


  1. ^ Jukes, Thomas H. Some historical notes on chlortetracycline. Reviews of Infectious Diseases 7(5):702-707 (1985).
  2. ^ Merck Veterinary Manual.