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Choluteca River near the city of Choluteca
|- location||Choluteca, Choluteca, Honduras|
|- elevation||0 m (0 ft)|
|Length||349 km (217 mi)|
|Basin||7,681 km2 (2,966 sq mi)|
The Choluteca River (Spanish: Río Grande o Choluteca) is a river in southern Honduras. Its source is in the Department of Francisco Morazán, near Lepaterique (south-west Tegucigalpa), and from there it flows north through the city of Tegucigalpa, then south through the department of El Paraíso, and the department and city of Choluteca. The mouth of the river - located among wetland - is near the coastal town of Cedeño, on the Gulf of Fonseca.
According to FAO, the Choluteca River has a length of 349 km from its source to its mouth. Its hydrographic basin has an area of 7,681 km².  It increases its volume between May and October, together with the rainy season. Its basin is affected by severe drought together with El Niño phenomenon, and this is usually associated with severe bush fires.
The flooding of this river was a major source of destruction in Hurricane Mitch in 1998. It washed out entire neighborhoods in Tegucigalpa, and eventually swelled to six times its normal size in Choluteca. There it destroyed neighborhoods and part of the commercial center. Further down it also devastated the tiny Morolica, where it not only destroyed the entire hamlet but nearly all its inhabitants died or disappeared.
- Rivers of Honduras
- Water Resources Management: The Choluteca river basin in Honduras
- Water Resources Management in Honduras
- "Honduras - Geografía y Población". FAO. 2000. Retrieved 2009-05-25.
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