RhoV (or Chp or Wrch2) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rho family of GTPases. Chp was identified in 1998 as a GTPase interacting with the p21 activated kinase PAK2. RhoV/Chp delineates with RhoU/Wrch a Rho subclass related to Rac and Cdc42, which emerged in early multicellular organisms during evolution. RhoV/Chp depends on palmitoylation rather than prenylation for association with plasma and intracellular membranes. In Xenopus embryos, RhoV is encoded by a canonical Wnt response gene and is induced in the developing neural crest at specification. RhoV activity cooperates with the Snai1 (Snail) transcription factor for the subsequent induction of the pro-invasive transcription factors Snai2 (Slug), Sox9 or Twist. 
^Aronheim A, Broder YC, Cohen A, Fritsch A, Belisle B and Abo A. (1998). "Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton". Curr Biol8 (20): 1125–8. doi:10.1016/S0960-9822(98)70468-3. ISSN0960-9822. PMID9778532.