Wörns made his professional debut in the Bundesliga at the young age of 17 years, 3 months and 30 days for Waldhof Mannheim and at the time, was the fourth youngest debutant ever. He played 18 games in his first season and 34 the next in the 2. Bundesliga.
The next year, he transferred to Bayer Leverkusen. Wörns quickly established himself as a defensive stalwart and anchored the strong Leverkusen defense for nearly a decade, together with sweeper Jens Nowotny and Markus Happe.
In 1998, he moved abroad to Paris SG in France. He failed to settle in and after one season transferred to Borussia Dortmund. He continued to play at Borussia Dortmund until he retired in 2008.
Wörns represented his country on 66 occasions and did not score.
Euro 1996: after an injury hit season, Wörns fails to get nominated and misses being on the winning squad.
World Cup 1998: Considered the best player on the German squad, Wörns played a stellar tournament until he fouled Davor Šuker in the 40th minute of the quarter-final match against Croatia to stop a possible breakaway run on goal following a lazy back pass by Lothar Matthäus. Though Wörns, realizing he's late, appeared to pull out of the tackle, contact was made with Šuker who fell theatrically, rolling several times on the ground. The German got a straight red card from Norwegian referee Rune Pedersen and three unanswered goals were scored against Germany after his sending off, making him the scapegoat for his country's 0–3 loss.
World Cup 2002: Wörns injures himself at the last moment, nonetheless Germany reached the final.
Euro 2004: Despite his strong performances against Holland and Latvia, he could not prevent Germany from crashing out in the initial group stage.