Cinchocaine

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Cinchocaine
Systematic (IUPAC) name
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Routes topical, intravenous (equine euthanasia)
Identifiers
CAS number 85-79-0 YesY
ATC code C05AD04 D04AB02 N01BB06 S01HA06 S02DA04
PubChem CID 3025
DrugBank APRD00915
ChemSpider 2917 YesY
UNII L6JW2TJG99 YesY
KEGG D00733 YesY
ChEBI CHEBI:247956 YesY
ChEMBL CHEMBL1086 YesY
Chemical data
Formula C20H29N3O2 
Mol. mass 343.463 g/mol
SMILES eMolecules & PubChem
 N (what is this?)  (verify)

Cinchocaine (or dibucaine) is an amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine [1].

Dibucaine is insoluble in alkaline aquatic environments.

It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.

[edit] See also

[edit] External links

  • Abdel-Ghani N, Youssef A, Awady M (2005). "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry.". Farmaco 60 (5): 419–24. doi:10.1016/j.farmac.2005.03.001. PMID 15910814. 
  • Souto-Padron T, Lima AP, de Oliveira Ribeiro R. (2006). "Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi.". Parasitol Res 99 (4): 317. doi:10.1007/s00436-006-0192-1. PMID 16612626. 
  • Nounou M, El-Khordagui L, Khalafallah N (2005). "Effect of various formulation variables on the encapsulation and stability of dibucaine base in multilamellar vesicles.". Acta Pol Pharm 62 (5): 369–79. PMID 16459486. 
  • Aroti,A.;Leontidis, E. (2001). Journal of Chemical Education 76: 786–788. 



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