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Cinchocaine (or Dibucaine) is an amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine [1].
Dibucaine is insoluble in alkaline aquatic enviromends.
It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.
[edit] External links
- Abdel-Ghani N, Youssef A, Awady M (2005). "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry.". Farmaco 60 (5): 419–24. doi:10.1016/j.farmac.2005.03.001. PMID 15910814.
- Souto-Padron T, Lima AP, de Oliveira Ribeiro R. (2006). "Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi.". Parasitol Res 99: 317. doi:10.1007/s00436-006-0192-1. PMID 16612626.
- Nounou M, El-Khordagui L, Khalafallah N. "Effect of various formulation variables on the encapsulation and stability of dibucaine base in multilamellar vesicles.". Acta Pol Pharm 62 (5): 369–79. PMID 16459486.
- Aroti,A.;Leontidis, E. (2001). Journal of Chemical Education 76: 786-788.
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Vasoprotectives (C05) |
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| Antihemorrhoidals for topical use |
corticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide)
local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine)
other ( Tribenoside)
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| Antivaricose therapy |
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| Capillary stabilising agents |
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