Cinnamtannin B1

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Cinnamtannin B1
Chemical structure of cinnamtannin B1
Identifiers
PubChem 475277
ChemSpider 417255
Jmol-3D images Image 1
Properties
Molecular formula C45H36O18
Molar mass 864.75 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Cinnamtannin B1 is a condensed tannin found in Cinnamomum verum. It is a type A proanthocyanidin.[1]

Cinnamon could have some pharmacological effects in the treatment of type 2 diabetes mellitus and insulin resistance. The plant material used in the study was mostly from Chinese cinnamon (see Chinese cinnamon's medicinal uses).[2][3] Recent studies in phytochemistry have indicated that cinnamtannin B1 isolated from C. Verum bears possible therapeutic effect on type 2 diabetes,[4] with the exception of the postmenopausal patients studied on Cinnamomum aromaticum.[5]

References[edit]

  1. ^ Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014. 
  2. ^ Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA (December 2003). "Cinnamon improves glucose and lipids of people with type 2 diabetes". Diabetes Care 26 (12): 3215–8. doi:10.2337/diacare.26.12.3215. PMID 14633804. 
  3. ^ Verspohl, Eugen J. et al.; Bauer, K; Neddermann, E (2005). "Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum In vivo and In vitro". Phytotherapy Research 19 (3): 203–206. doi:10.1002/ptr.1643. PMID 15934022. 
  4. ^ Taher, Muhammad et al.. "A proanthocyanidin from Cinnamomum zeylanicum stimulates phosphorylation of insullin receptor in 3T3-L1 adipocyties" (PDF). Retrieved 2008-05-11. 
  5. ^ Vanschoonbeek, Kristof et al.. "Cinnamon Supplementation Does Not Improve Glycemic Control in Postmenopausal Type 2 Diabetes Patients". Retrieved 2008-05-11.