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Claudia Colla (died 1611), was an alleged Italian witch and the royal mistress of the sovereign Ranuccio I Farnese, Duke of Parma.
Colla belonged to the Parmesan merchant class. In 1599, her royal lover Farnese married Margherita Aldobrandini. After a decade of childless marriage, Farnese accused Claudia Colla and her mother Elena for having caused the lack of offspring by the use of sorcery. The accusation of sorcery was unusual for someone of her class. She was judged guilty and sentenced to be executed by burning.