Climbazole
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| Systematic (IUPAC) name | |
| (RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one [1] | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | topical |
| Identifiers | |
| CAS number | 38083-17-9 |
| ATC code | None |
| UNII | 9N42CW7I54  |
| Chemical data | |
| Formula | C15H17ClN2O2 |
| Mol. mass | 292.76 |
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Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff[2] and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff.[2] Its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole.
[edit] Indications and formulations
It is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.
[edit] Side effects
May cause localized irritation of the skin with symptoms including redness, rashes and itching.[citation needed]
[edit] References
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