Clonitazene

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Clonitazene
Clonitazene.png
Systematic (IUPAC) name
2-[2-[(4-chlorophenyl)methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
Clinical data
Identifiers
3861-76-5
None
PubChem CID 62528
DrugBank DB01523 YesY
ChemSpider 56301 YesY
UNII S90R21A2V2 YesY
ChEMBL CHEMBL2104616
Synonyms Clonitazene
Chemical data
Formula C20H23ClN4O2
386.88 g/mol
 YesY (what is this?)  (verify)

Clonitazene is an opioid analgesic of approximately three times the potency of morphine.[citation needed] It is related to etonitazene, an opioid of significantly higher potency. Clonitazene is not currently marketed. It is a controlled substance; in the United States it is a Schedule I Narcotic controlled substance with a DEA ACSCN of 9612 and an annual manufacturing quota of zero.

Synthesis[edit]

Clonitrazine synthesis:[1] Hoffmann et al., U.S. Patent 2,935,514 (1960 to Ciba).

References[edit]

  1. ^ Hunger, A.; Kebrle, J.; Rossi, A.; Hoffmann, K. (1957). "Synthese basisch substituierter, analgetisch wirksamer Benzimidazol-Derivate". Experientia 13 (10): 400. doi:10.1007/BF02161116.  edit