Coccidioides posadasii is a pathogenic fungus that, along with Coccidioides immitis, is the causative agent of coccidioidomycosis, or Valley fever in humans. It resides in the soil in certain parts of the Southwestern United States, northern Mexico, and some other areas in the Americas, however, its evolution was connected to its animal hosts.
C. posadasii and C. immitis are morphologically identical but genetically and epidemiologically distinct. C. posadasii was identified as a separate species other than C. immitis in 2002 after a phylogenetic analysis. The two species can be distinguished by DNA polymorphisms and different rates of growth in the presence of high-salt concentrations: C. posadasii grows more slowly. It is also differs epidemiologically, since it is found outside the San Joaquin Valley. Unlike its relative C. immitis, which is geographically largely limited to California, C. posadasii can also be found in northern Mexico and South America.
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- Sharpton, T. J., Stajich, J. E., Rounsley, S. D., et al. (October 2009). "Comparative Genomic Analyses of the Human Fungal Pathogens Coccidioides and Their Relatives". Genome Research 19 (10): 1722–31.
- Miranda, Elizabeth (2011). "Coccidioides posadasii". The Encyclopedia of Life (EOL). eol.org. Retrieved 17 July 2013.
- Fisher, M. C., Koenig, G. L., White, T. J., & Taylor, J. W (2002). "Molecular and phenotypic description of Coccidioides posadasii sp. nov., previously recognized as the non-California population of Coccidioides immitis". Mycologia 94 (1): 73–84.
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