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Cochliomyia hominivorax, the New World screw-worm fly, or screw-worm for short, is a species of parasiticfly that is well known for the way in which its larvae (maggots) eat the living tissue of warm-bloodedanimals. It is present in the New World tropics. There are five species of Cochliomyia but only one species of screw-worm fly in the genus; there is also a single Old World species in a different genus (Chrysomya bezziana). Infestation of a live vertebrate animal by a maggot is technically called myiasis. While the maggots of many fly species eat dead flesh, and may occasionally infest an old and putrid wound, screw-worm maggots are unusual because they attack healthy tissue. Screw-worms are a reportable species to the state veterinarian in the United States if discovered on livestock.
Screw-worm females lay 250-500 eggs in the exposed flesh of warm-blooded animals, including humans, such as in wounds and the navels of newly-born animals. The larvae hatch and burrow into the surrounding tissue as they feed. If the wound is disturbed during this time the larvae burrow or "screw" deeper into the flesh, which is the source of the insect's name. The maggots are capable of causing severe tissue damage or even death to the host. Approximately three to seven days after hatching the larvae fall to the ground to pupate. The pupae reach the adult stage about seven days later. Female screw-worm flies mate four to five days after hatching. The entire life cycle is approximately twenty days. A female can lay up to 3,000 eggs and fly up to 200 km (120 mi) during her life.