CodY protein family

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PDB 2b0l EBI.jpg
c-terminal dna binding domain of transcriptional pleiotropic repressor cody.
Symbol CodY
Pfam PF06018
Pfam clan CL0161
InterPro IPR010312

In molecular biology, the CodY protein family consists of several bacterial GTP-sensing transcriptional pleiotropic repressor CodY proteins. CodY has been found to repress the dipeptide transport operon (dpp) of Bacillus subtilis in nutrient-rich conditions.[1] The CodY protein also has a repressor effect on many genes in Lactococcus lactis during growth in milk.[2]


  1. ^ Slack FJ, Serror P, Joyce E, Sonenshein AL (February 1995). "A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon". Mol. Microbiol. 15 (4): 689–702. doi:10.1111/j.1365-2958.1995.tb02378.x. PMID 7783641. 
  2. ^ Guedon E, Serror P, Ehrlich SD, Renault P, Delorme C (June 2001). "Pleiotropic transcriptional repressor CodY senses the intracellular pool of branched-chain amino acids in Lactococcus lactis". Mol. Microbiol. 40 (5): 1227–39. doi:10.1046/j.1365-2958.2001.02470.x. PMID 11401725. 

This article incorporates text from the public domain Pfam and InterPro IPR010312