Codoxime

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Codoxime
Codoxime.svg
Systematic (IUPAC) name
(((4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-ylidene)amino)oxy)acetic acid
Clinical data
Legal status Narcotic Schedule I (UN)
Identifiers
CAS number 7125-76-0
ATC code None
PubChem CID 9570253
ChemSpider 7844721
UNII JT5I2F57F7 YesY
KEGG D03581
Synonyms Codoxime
Chemical data
Formula C20H24N2O5 
Mol. mass 372.415 g/mol

Codoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects[1] and was found to have moderate potential to cause dependence in animal studies.[2]

References[edit]

  1. ^ Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042
  2. ^ Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586