Buzzell grew up in San Ramon, California and enlisted in the United States Army at the age of 26. Prior to joining the Army he described his life as engaging in a lot of drinking, drug use, dead-end jobs and a minor criminal record. He was very optimistic about his Army service and was determined to follow the Army recruiting slogan of "Be All That You Can Be". He joined the service as an infantryman and spent 2003 - 2004 in Iraq, assigned to a Stryker Brigade Combat Team. In his book he expresses a great deal of enthusiasm about the benefits of wheels over traditional treaded armor in urban settings.
It was in Iraq that Buzzell began publishing a blog under the title "CBFTW", "Colby Buzzel Fuck The War", as a replacement for his habitual journaling back in the States. The blog  gained popularity quickly, because as an anonymous blogger, Buzzell was able to share more lucid experiences than an embedded journalist, and he was also able to share a bit more of the truth than the Army was able to.
Buzzell's blog gained recognition for its realistic portrayal of gripping first hand accounts of the war in Iraq. This 'milblog' won praise as “an unfiltered, often ferocious expression of his boots-on-the-ground view of the Iraq war" 
Colby published a book on his experiences entitled, My War: Killing Time in Iraq combining narrative, blog entries, and emails that evolved from his blog over time. The book received good reviews and has been recommended for public libraries .
In 2008, Buzzell was re-called for active duty. After he arrived at his post, he was examined by the medical staff at Fort Benning, and marked "not deployable" due to post-traumatic stress disorder.
In 2011, Buzzell published the book Lost in America: A Dead End Journey, under HarperCollins about coping with his post traumatic stress disorder by taking a road trip to no where, all the while thinking about his newborn son, wife, and recently deceased mother.
- Griggs, Brandon (2008-11-13). "Soldier finds his voice blogging from Iraq". CNN.com. Retrieved 2008-11-13.
- Memmott, Mark (2005-05-11). "'Milbloggers' are typing their place in history". USA TODAY. Retrieved 2008-11-13.
- "Ex-GI’s memoir named best book based on blog". MSNBC.com. 2007-05-15. Retrieved 2008-11-13.
- Buzzell, Colby (2008-05-08). "Return to Sender - Iraq Veteran Gets the Call Again". San Francisco Chronicle. pp. B7. Retrieved 2008-11-13.
- Buzzell, Colby (2008-09-08). "The Army Wants You...Again! (Yes, Really.)". Esquire. p. 172. Retrieved 2008-11-13.
- Colby Buzzell's blog
- 3d Stryker Brigade, Fort Lewis Washington
- Interview on Radio Allegro
- Interview with Colby Buzzell