Cold shock response
Myth of sudden hypothermia
In humans, cold shock response is perhaps the most common cause of death from immersion in very cold water, such as by falling through thin ice. The cold water can cause heart attack due to vasoconstriction, the heart has to work harder to pump the same volume of blood throughout the body. For people with heart disease, this additional workload can cause the heart to go into arrest. Inhalation of water (and thus drowning) may result from hyperventilation. Some people, due to body type or mental conditioning, are much better able to survive swimming in very cold water.
Hypothermia from exposure to cold water is not as sudden as is often believed. A person who survives the initial minute of trauma (after falling into icy water), can survive for at least thirty minutes provided they don't drown. However, the ability to perform useful work (for example to save oneself) declines substantially after 10 minutes (as the body protectively cuts off blood flow to "non-essential" muscles).
It is possible to undergo physiological conditioning to reduce the cold shock response, and some people are naturally better suited to swimming in very cold water. Adaptations include the following: (1) having an insulating layer of body fat covering the limbs and torso without being overweight; (2) ability to experience immersion without involuntary physical shock or mental panic; (3) ability to resist shivering; (4) ability to raise metabolism (and, in some cases, increase blood temperature slightly above the normal level; (5) a slight but significant ability to mentally control blood flow to the muscles: and (6) a generalized delaying of metabolic shutdown (including slipping into unconsciousness) as central and peripheral body temperatures fall. In these ways, winter swimmers can survive both the initial shock and prolonged exposure. Nevertheless, the human organism is limited by its thermal design: in freezing water, the struggle to maintain blood temperature (by swimming or conditioned metabolic response) produces great fatigue after 30 minutes or less.
Cold shock response in bacteria
Bacteria express a well-defined set of proteins after a rapid decrease in temperature, which differ from those expressed under heat shock conditions. Cold shock proteins may include helicases, nucleases, and ribosome-associated components that interact with DNA and RNA. Processes such as cold signal perception, membrane adaptation, and the modification of the translation apparatus are involved.
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