Collagen, type XIX, alpha 1

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Collagen, type XIX, alpha 1
Identifiers
Symbols COL19A1 ; COL9A1L; D6S228E
External IDs OMIM120165 MGI1095415 HomoloGene55608 GeneCards: COL19A1 Gene
RNA expression pattern
PBB GE COL19A1 211011 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1310 12823
Ensembl ENSG00000082293 ENSMUSG00000026141
UniProt Q14993 Q0VF58
RefSeq (mRNA) NM_001858 NM_007733
RefSeq (protein) NP_001849 NP_031759
Location (UCSC) Chr 6:
70.58 – 70.92 Mb
Chr 1:
24.26 – 24.59 Mb
PubMed search [1] [2]

Collagen alpha-1(XIX) chain is a protein that in humans is encoded by the COL19A1 gene.[1][2][3]

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced.[3]

References[edit]

  1. ^ Myers JC, Sun MJ, D'Ippolito JA, Jabs EW, Neilson EG, Dion AS (Mar 1993). "Human cDNA clones transcribed from an unusually high-molecular-weight RNA encode a new collagen chain". Gene 123 (2): 211–7. doi:10.1016/0378-1119(93)90126-N. PMID 7916703. 
  2. ^ Gerecke DR, Olson PF, Koch M, Knoll JH, Taylor R, Hudson DL, Champliaud MF, Olsen BR, Burgeson RE (Jul 1997). "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13". Genomics 41 (2): 236–42. doi:10.1006/geno.1997.4638. PMID 9143499. 
  3. ^ a b "Entrez Gene: COL19A1 collagen, type XIX, alpha 1". 

Further reading[edit]