Collapsin response mediator protein family
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Collapsin response mediator protein family or CRMP family consists of five intracellular phosphoproteins (CRMP1, CRMP2, CRMP3, CRMP4, CRMP5) of similar molecular size (60–66 kDa) and high (50–70%) amino acid sequence identity. CRMPs are predominantly expressed in the nervous system during development[1] and are parts to the mechanism underlying the repulsive guidance of growth cones.
[edit] References
- ^ Charrier E, Reibel S, Rogemond V, Aguera M, Thomasset N, Honnorat J (August 2003). "Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders". Mol. Neurobiol. 28 (1): 51–64. doi:10.1385/MN:28:1:51. PMID 14514985.
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