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It has been suggested that the use of naloxone and flumazenil be administered more selectively than glucose and thiamine.
Some have proposed that the concept be abandoned.
- Bartlett D (December 2004). "The coma cocktail: indications, contraindications, adverse effects, proper dose, and proper route". J Emerg Nurs 30 (6): 572–4. doi:10.1016/j.jen.2004.09.002. PMID 15565045.
- Doyon S, Roberts JR (May 1994). "Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine". Emerg. Med. Clin. North Am. 12 (2): 301–16. PMID 8187685.
- Buylaert WA (December 2000). "Coma induced by intoxication". Acta Neurol Belg 100 (4): 221–4. PMID 11233676.
- Bledsoe BE (November 2002). "No more coma cocktails. Using science to dispel myths & improve patient care". Journal of Emergency Medical Services 27 (11): 54–60. PMID 12483195.
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