|Basin countries||United States|
|Mouth elevation||1181 feet (360 meters)|
|River system||Allegheny River|
The creek's drainage covers much of southeastern Chautauqua County, New York and southwestern Cattaraugus County, New York. The creek's most notable tributary is the Chadakoin River, which supplies the creek water from Chautauqua Lake. Its watershed is bounded by the Chautauqua Ridge, a continental divide.
Conewango Creek joins the Allegheny River at the city of Warren, Pennsylvania.
On September 26, 2009 an obsolete Civil War-era low head dam within the city of Warren on the Conewango Creek was removed. Removal of this dam will allow fish migration from the Allegheny River throughout the upper reaches of the Conewango Creek drainage basin. 
- List of rivers of New York
- List of rivers of Pennsylvania
- List of tributaries of the Allegheny River