Because of her husband's 2006 senate campaign, Schultz took a leave of absence from The Plain Dealer to campaign for his election. She returned to The Plain Dealer in January 2007. On September 19, 2011, Schultz again resigned from The Plain Dealer, having written in a note to colleagues that "in recent weeks, it has become painfully clear that my independence, professionally and personally, is possible only if I’m no longer writing for the newspaper that covers my husband’s senate race on a daily basis".
Schultz's first book, Life Happens: And Other Unavoidable Truths—a collection of her previously published columns, was printed in 2006. Her second book, ... and His Lovely Wife: A Memoir from the Woman Beside the Man—a journal of her experiences on the campaign trail, was released in 2007.
Ms. Schultz also writes a column, called "Views" for PARADE magazine. On July 13, 2009, she appeared on CBS The Late Late Show with Craig Ferguson. She has contributed to the online political blog The Huffington Post.