In molecular biology, the copper type II ascorbate-dependent monooxygenases are a class of enzymes that require copper as a cofactor and which use ascorbate as an electron donor. This family contains two related enzymes, dopamine beta-monooxygenase EC 126.96.36.199 and peptidylglycine alpha-amidating monooxygenase EC 188.8.131.52. There are a few regions of sequence similarities between these two enzymes, two of these regions contain clusters of conserved histidine residues which are most probably involved in binding copper.
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This article incorporates text from the public domain Pfam and InterPro IPR000323