Anionic form of α-
Neutral form of α-
Molecular formula C
6H 13O 9P
Molar mass 260.14 g mol
Except where noted otherwise, data are given for materials in their
standard state (at 25 °C (77 °F), 100 kPa)
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Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon. It can exist in either the α- or β- anomeric form.
Reactions of α-glucose 1-phosphate [ edit ]
Catabolic [ edit ]
glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.
To be utilized in cellular catabolism it must first be converted to
glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.
Anabolic [ edit ]
glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.
β-Glucose 1-phosphate [ edit ]
β-Glucose 1-phosphate is found in some microbes. It is produced by inverting α-glucan phosphorylases including
maltose phosphorylase, kojibiose phosphorylase and trehalose phosphorylase and is then converted into glucose 6-phosphate by β-phosphoglucomutase.
See also [ edit ]