Coronary perfusion pressure
Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure, meaning the difference between the aortic diastolic pressure and left ventricular end-diastolic pressure. It is a term used mainly in research concerning cardiac arrest. In this context, it is assumed that the minimum CPP needed for a successful outcome is 15mm Hg.
CPP is a part of normal blood pressure that is specifically responsible for coronary blood flow. CPP is also, generally, a surrogate term for coronary blood flow.
During cardiac arrest, CPP is one of the most important variables associated with the likelihood of return of spontaneous circulation (ROSC), the restoration of a pulse. A CPP of at least 15 mmHg is thought to be necessary for ROSC.
- Disorders of circulatory flow. In The ICU Book. Lipincott Williams and Wilkins, 2007, p. 287
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